• raftkevin6 posted an update 2 months, 2 weeks ago

    Xao tam phan (Paramignya trimera (Oliv.) Guillaum) can be a Vietnamese traditionally medicinal plant employed in treating numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This study aimed to analyze the end results of 5 various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The outcomes indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the maximum antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (apart from total flavonoids) and antioxidant capacity, in comparison with conventional and ultrasound-assisted extractions. These data reveal that using methanol and microwave-assisted extraction are recommended for extraction of biologically active phytochemicals from P. trimera root for application inside the nutraceutical and/or pharmaceutical industries.

    Drying methods, solvents and extraction methods greatly affect the phytochemical compounds and biological activity from plant materials. The aims with this study could determine the end results of drying methods, various solvents and extraction methods around the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root obtained from Vietnam. The final results showed that microwave drying was an efficient method in removal of water regarding shortest drying time, lowest energy consumption and greatest retention of phytochemical compounds and antioxidant capacity from the P. trimera root while methanol and microwave-assisted extraction were the best solvent and way of greatest extraction of the phytochemical compounds and antioxidant capacity in the P. trimera root. The findings out of this study allow retaining the greatest degrees of phytochemical compounds and antioxidant capacity through the P. trimera root for potential application from the nutraceutical industry.

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