• raftkevin6 posted an update 2 months, 2 weeks ago

    Xao tam phan (Paramignya trimera (Oliv.) Guillaum) can be a Vietnamese traditionally medicinal plant employed in treating numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This research aimed to look into the end results of 5 various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The final results indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the maximum antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (aside from total flavonoids) and antioxidant capacity, when compared with conventional and ultrasound-assisted extractions. These data reveal that the application of methanol and microwave-assisted extraction are suggested for extraction of biologically active phytochemicals from P. trimera root for application within the nutraceutical and/or pharmaceutical industries.

    Drying methods, solvents and extraction methods greatly modify the phytochemical compounds and biological activity from plant materials. The aims on this study were to determine the consequences of numerous drying methods, various solvents and extraction methods for the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root purchased from Vietnam. The results demonstrated that microwave drying was an efficient method in removal of water with regards to shortest drying time, lowest energy consumption and greatest retention of phytochemical compounds and antioxidant capacity through the P. trimera root while methanol and microwave-assisted extraction were the best solvent and method for greatest extraction from the phytochemical compounds and antioxidant capacity in the P. trimera root. The findings from this study allow retaining the greatest amounts of phytochemical compounds and antioxidant capacity from the P. trimera root for potential application from the nutraceutical industry.

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