• raftkevin6 posted an update 4 months, 2 weeks ago

    Xao tam phan (Paramignya trimera (Oliv.) Guillaum) can be a Vietnamese traditionally medicinal plant used in treating numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This research aimed to investigate the end results of 5 various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The results indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the best antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (with the exception of total flavonoids) and antioxidant capacity, when compared to conventional and ultrasound-assisted extractions. These data show using methanol and microwave-assisted extraction are suggested for extraction of biologically active phytochemicals from P. trimera root for application from the nutraceutical and/or pharmaceutical industries.

    Drying methods, solvents and extraction methods greatly modify the phytochemical compounds and biological activity from plant materials. The aims of this study could determine the consequences of drying methods, various solvents and extraction methods on the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root extracted from Vietnam. The results indicated that microwave drying was an efficient method in removal of water in terms of shortest drying time, lowest energy consumption and greatest retention of phytochemical compounds and antioxidant capacity from the P. trimera root while methanol and microwave-assisted extraction were the most effective solvent and way for greatest extraction of the phytochemical compounds and antioxidant capacity through the P. trimera root. The findings from this study allow retaining the best numbers of phytochemical compounds and antioxidant capacity in the P. trimera root for potential application within the nutraceutical industry.

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